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      https://www.ias.ac.in/article/fulltext/jbsc/043/03/0437-0445

    • Keywords

       

      Dynein; fluorescence; kinesin; motor proteins; myosin

    • Abstract

       

      Long-distance transport of many organelles inside eukaryotic cells is driven by the dynein and kinesin motors onmicrotubule filaments. More than 30 years since the discovery of these motors, unanswered questions include motor–organelle selectivity, structural determinants of processivity, collective behaviour of motors and track selection within thecomplex cytoskeletal architecture, to name a few. Fluorescence microscopy has been invaluable in addressing some of thesequestions. Here we present a review of some efforts to understand these sub-microscopic machines using fluorescence.

    • Author Affiliations

       

      DIVYA PATHAK1 SHREYASI THAKUR2 ROOP MALLIK1

      1. Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India
      2. Department of Physiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    • Dates

       
  • Journal of Biosciences | News

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      Posted on July 25, 2019

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