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    • Keywords


      Dynein; fluorescence; kinesin; motor proteins; myosin

    • Abstract


      Long-distance transport of many organelles inside eukaryotic cells is driven by the dynein and kinesin motors onmicrotubule filaments. More than 30 years since the discovery of these motors, unanswered questions include motor–organelle selectivity, structural determinants of processivity, collective behaviour of motors and track selection within thecomplex cytoskeletal architecture, to name a few. Fluorescence microscopy has been invaluable in addressing some of thesequestions. Here we present a review of some efforts to understand these sub-microscopic machines using fluorescence.

    • Author Affiliations



      1. Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India
      2. Department of Physiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    • Dates

  • Journal of Biosciences | News

      Forthcoming Special issue.

    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".

      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.

      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.

      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

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