• Insights into brain development and disease from neurogenetic analyses in Drosophila melanogaster

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      https://www.ias.ac.in/article/fulltext/jbsc/039/04/0595-0603

    • Keywords

       

      Asymmetric division; lineage; neuroblast; SWI/SNF complex; transit amplifying cell; tumour

    • Abstract

       

      Groundbreaking work by Obaid Siddiqi has contributed to the powerful genetic toolkit that is now available for studying the nervous system of Drosophila. Studies carried out in this powerful neurogenetic model system during the last decade now provide insight into the molecular mechanisms that operate in neural stem cells during normal brain development and during abnormal brain tumorigenesis. These studies also provide strong support for the notion that conserved molecular genetic programs act in brain development and disease in insects and mammals including humans.

    • Author Affiliations

       

      Heinrich Reichert1

      1. Biozentrum, University of Basel, Basel, Switzerland
    • Dates

       
  • Journal of Biosciences | News

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      Posted on July 25, 2019

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