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      https://www.ias.ac.in/article/fulltext/jbsc/039/01/0013-0027

    • Keywords

       

      Biochemistry; biological design; evolution; LUCA; NAD; RNA world

    • Abstract

       

      Biochemical information has been crucial for the development of evolutionary biology. On the one hand, the sequence information now appearing is producing a huge increase in the amount of data available for phylogenetic analysis; on the other hand, and perhaps more fundamentally, it allows understanding of the mechanisms that make evolution possible. Less well recognized, but just as important, understanding evolutionary biology is essential for understanding many details of biochemistry that would otherwise be mysterious, such as why the structures of NAD and other coenzymes are far more complicated than their functions would seem to require. Courses of biochemistry should thus pay attention to the essential role of evolution in selecting the molecules of life.

    • Author Affiliations

       

      Athel Cornish-Bowden1 Juli Peretó2 María Luz Cárdenas1

      1. Unité de Bioénergétique et Ingénierie des Protéines, Centre National de la Recherche Scientifique, Aix-Marseille Université, 31 chemin Joseph-Aiguier, 13402 Marseille Cedex 20, France
      2. Departament de Bioquímica i Biologia Molecular, Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, Valencia, Spain
    • Dates

       
  • Journal of Biosciences | News

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