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      https://www.ias.ac.in/article/fulltext/jbsc/037/06/0989-0998

    • Keywords

       

      Gastrointestinal tract; gut microbiota; mode of delivery; 16S rRNA

    • Abstract

       

      In this study fecal microflora of human infants born through vaginal delivery (VB) and through cesarean section (CB) were investigated using culture-independent 16S rDNA cloning and sequencing approach. The results obtained clearly revealed that fecal microbiota of VB infants distinctly differ from those in their counterpart CB infants. The intestinal microbiota of infants delivered by cesarean section appears to be more diverse, in terms of bacteria species, than the microbiota of vaginally delivered infants. The most abundant bacterial species present in VB infants were Acinetobacter sp., Bifidobacterium sp. and Staphylococcus sp. However, CB infant’s fecal microbiota was dominated with Citrobacter sp., Escherichia coli and Clostridium difficile. The intestinal microbiota of cesarean section delivered infants in this study was also characterized by an absence of Bifidobacteria species. An interesting finding of our study was recovery of large number of Acinetobacter sp. consisting of Acinetobacter pittii (former Acinetobacter genomic species 3), Acinetobacter junii and Acinetobacter baumannii in the VB infants clone library. Among these, Acinetobacter baumannii is a known nosocomial pathogen and Acinetobacter pittii (genomic species 3) is recently recognized as clinically important taxa within the Acinetobacter calcoaceticusAcinetobacter baumannii (ACB) complex. Although none of the infants had shown any sign of clinical symptoms of disease, this observation warrants a closer look.

    • Author Affiliations

       

      Prashant Kumar Pandey1 Pankaj Verma1 Himanshu Kumar1 Ashish Bavdekar2 Milind S Patole1 Yogesh S Shouche1

      1. Insect Molecular Biology Unit, National Centre for Cell Science, Pune 411 007
      2. Department of Paeditrics, KEM Hospital, Pune 411 011
    • Dates

       
  • Journal of Biosciences | News

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