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    • Keywords


      Apoptosis; endophytic fungus; Fusarium solani; paclitaxel

    • Abstract


      A fungus was isolated from the stem cuttings of Taxus celebica, which produced paclitaxel in liquid-grown cultures. The fungus was identified as Fusarium solani based on colony characteristics, morphology of conidia and the 26S rDNA sequence. Paclitaxel was identified by chromatographic and spectroscopic comparison with authentic paclitaxel and its cytotoxic activity towards Jurkat cells in vitro.

    • Author Affiliations


      B V S K Chakravarthi1 Prasanta Das2 Kalpana Surendranath1 Anjali A Karande1 Chelliah Jayabaskaran1

      1. Department of Biochemistry, Indian Institute of Science, Bangalore 560 012, India
      2. Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore 560 012, India
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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