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    • Blood coagulation factor VIII: An overview

      G M Bhopale R K Nanda

      Review Volume 28 Issue 6 December 2003 pp 783-789

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/028/06/0783-0789

    • Keywords

       

      Blood coagulation factor VIII; hemophilia A; replacement therapy

    • Abstract

       

      Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the clinician should be interested.

    • Author Affiliations

       

      G M Bhopale1 R K Nanda1

      1. Research and Development Division, Hindustan Antibiotics Ltd., Pimpri, Pune - 411 018, India

    • Dates

       
      Published
      December 2003
      Manuscript received
      30 April 2003
      Accepted
      17 November 2003

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