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      https://www.ias.ac.in/article/fulltext/jbsc/026/02/0205-0215

    • Keywords

       

      Echo-planar imaging; finger tapping frequency; functional demand; functional magnetic resonance imaging; primary motor cortex

    • Abstract

       

      Functional magnetic resonance imaging (fMRI) studies have been performed on 20 right handed volunteers at 1.5 Tesla using echo planar imaging (EPI) protocol. Index finger tapping invoked localized activation in the primary motor area. Consistent and highly reproducible activation in the primary motor area was observed in six different sessions of a volunteer over a period of one month. Increased tapping rate resulted in increase in the blood oxygenation level dependent (BOLD) signal intensity as well as the volume/area of activation (pixels) in the contra-lateral primary motor area up to tapping rate of 120 taps/min (2 Hz), beyond which it saturates. Activation in supplementary motor area was also observed. The obtained results are correlated to increased functional demands.

    • Author Affiliations

       

      S Khushu1 S S Kumaran1 R P Tripathi1 A Gupta1 P C Jain2 V Jain3 4

      1. NMR Research Centre, Institute of Nuclear Medicine and Allied Sciences, Lucknow Road, Delhi - 110 054, India
      2. Department of Physics and Astrophysics, University of Delhi, Delhi - 110 007, India
      3. BR Ambedkar Centre for Biomedical Research, University of Delhi, Delhi - 110 007, India
      4. Wallace-Kettering Neuroscience Institute, Kettering Medical Centre and Department of Emergency Medicine, Wright State University, Kettering, OH - 45429, USA

    • Dates

       
      Published
      June 2001
      Manuscript received
      2 November 2000
      Accepted
      18 April 2001

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