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      https://www.ias.ac.in/article/fulltext/jbsc/023/05/0601-0604

    • Keywords

       

      HLA; anti HLA antibodies; antenatal sera

    • Abstract

       

      Antenatal sera from 1334 pregnant women attending the Nowrojee B J Wadia Maternity Hospital and KEM Hospital in Parel, Mumbai were collected and screened for anti HLA A and B antibodies to produce an indigenous HLA tissue typing tray. One hundred and sixty three sera (12.2%) were found positive for HLA antibodies. Nonetheless, the percentage of positive sera were almost the same in women of different parity. Moreover, the incidence of anti-HLA antibodies was correlated with the allelic frequencies in the Maharastrian population. Thus in India, collection and screening of sera from pregnant females is a simple and cost-effective method of acquiring polyclonal sera for routine use in tissue typing.

    • Author Affiliations

       

      U Shankarkumar1 S C Gupte1 S S Gupte1 S V Pednkar1 K Ghosh1 D Mohanty1

      1. HLA Department, Institute of Immunohaematology, 13th Floor, New MS Building, KEM Hospital Campus, Parel, Mumbai - 400 012, India
    • Dates

       
  • Journal of Biosciences | News

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