• Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/023/03/0177-0184

    • Keywords

       

      Morphogenesis; slime moulds; patterning

    • Abstract

       

      We showed previously that ifDictyostelium discoideum cells are sucked up into a small glass capillary with air at one end and plugged with mineral oil at the other, a sharp band of fast moving cells with prestalk characteristics formed within a minute at the air end of the cell mass. We now demonstrate that oxygen inside the capillary is responsible for the initiation and positioning of the sharp division line between prestalk-like and prespore-like cells, and that the length of the prestalk zone is regulated by the oxygen concentration. Our results are compared to a quantitative theory, showing good agreement with the experiments. We also discuss the relevance of these observations to the differentiation of prestalk and prespore zones in normal slugs and the origins of polarity in this organism.

    • Author Affiliations

       

      J T Bonner1 Lee Segel1 2 Edward C Cox1 3

      1. Department of Ecology and Evolution, Princeton University, Princeton, NJ - 08544, USA
      2. Department of Applied Mathematics and Computer Science, The Weizmann Institute of Science, Rehovot - 76100, Israel
      3. Department of Molecular Biology, Princeton University, Princeton, NJ - 08544, USA
    • Dates

       
  • Journal of Biosciences | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2017-2019 Indian Academy of Sciences, Bengaluru.