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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/018/03/0373-0380

    • Keywords

       

      HLA; anti-HLA antibodies; post-partum; pregnancy

    • Abstract

       

      Sera from 4088 pregnant women (649 antenatal bleeding and 3439 post-partum bleeding) living in Madurai, were collected and screened for anti-HLA. A, B and DR antibodies. 696 of them were screened for anti-HLA DR antibodies. Ten per cent (65/649) of antenatal sera and 13 4% of post-partum sera (463/3439) were positive for HLA A and B antibodies: nonetheless the percentage of monospecific sera were almost the same in both. Screening for HLA DR antibodies were carried out using platelet absorption in test tray technique: seventy three of 696 (10.5%) were positive. The incidence of anti-HLA A, B antibodies correlates to the allelic frequencies in the population. Thus in India, collection and screening post-partum haemorrhage is the simplest and cost effective method of acquiring polyclonal sera for routine laboratory and diagnostic use.

    • Author Affiliations

       

      R M Pitchappan1 S Amutha1 V Mahendran1 V Brahmajothi1 U Shankar Kumar1 K Balakrishnan1 R Shantha Kumari1 M Sashidhar1 SamalRaj1 May Manuel1 2 V Indra Raja1 3

      1. Unit of Immunogenetics, School of Biological Sciences, Madurai Kamaraj University, Madurai - 625 021, India
      2. Department of Obstetrics and Gynaecology, Government Rajaji Hospital, Madurai - 625 002, India
      3. Christian Mission Hospital, East Veli Street, Madurai - 625 001, India

    • Dates

       
      Published
      September 1993
      Manuscript received
      7 August 1992
      Manuscript revised
      3 June 1993

  • Journal of Biosciences | News

      Forthcoming Special issue.


    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".


      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.


      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.


      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

      Posted on April 12, 2023
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