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      https://www.ias.ac.in/article/fulltext/jbsc/017/04/0395-0411

    • Keywords

       

      Genome mapping; DNA sequence analysis; fractal; chaos game representation; mitochondrial genomes; Mycobacterium ; nucleotide sequences

    • Abstract

       

      In this article we describe and demonstrate the versatility of a computer program, GENOME MAPPING, that uses interactive graphics and runs on an IRIS workstation. The program helps to visualize as well as analyse global and local patterns of genomic DNA sequences. It was developed keeping in mind the requirements of the human genome sequencing programme, which requires rapid analysis of the data. Using GENOME MAPPING one can discern signature patterns of different kinds of sequences and analyse such patterns for repetitive as well as rare sequence strings. Further, one can visualize the extent of global homology between different genomic sequences. An application of our method to the published yeast mitochondrial genome data shows similar sequence organizations in the entire sequence and in smaller subsequences

    • Author Affiliations

       

      Pradeep Kumar Burma1 Alok Raj1 2 Jayant K Deb1 2 Samir K Brahmachari1

      1. Molecular Biophysics Unit, Indian Institute of Science, Bangalore - 560 012, India
      2. Department of Computer Engineering, Birla Institute of Technology, Mesra, Ranchi - 835 215
    • Dates

       
  • Journal of Biosciences | News

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