Coupling of proteins to liposomes and their role in understanding delayed type of hypersensitivity in human and mice
U Sengupta Sudhir Sinha V Chaturvedi R B Narayanan Sreevatsa C M Gupta
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Liposome-coupled lepromin was found to elicit a 3-week skin reaction in leprosy patients similar to that elicited by wholeMycobacterium leprae. The present study suggests that the presentation of antigens in a specific orientation is necessary for evoking delayed type hypersensitivity response in humans.
U Sengupta1 Sudhir Sinha1 V Chaturvedi1 R B Narayanan1 2 Sreevatsa1 C M Gupta1 3
Volume 48, 2023
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