• Fulltext


        Click here to view fulltext PDF

      Permanent link:

    • Keywords


      Mitochondrial carriers; kinetics; ping-pong mechanism

    • Abstract


      The single-binding site or ping-pong mechanism is widely accepted for exchange reactions, catalysed by mitochondrial carriers.

      However, when the most relevant approach to discriminate between mechanisms,i.e., kinetic study is used, the ping-pong mechanism is eliminated in favour of the sequential or ternary complex mechanism implying two binding sites simultaneously accessible to both internal and external substrates. This is the case for the oxoglutarate carrier, the aspartate/glutamate carrier and there are very strong presumptive evidences for the adenylic carrier.

    • Author Affiliations


      F E Sluse1 A Evens1 C Duyckaerts1 C M Sluse-Goffart1

      1. Laboratory of Bioenergetics, University of Liége, Place du 20-AoŬt 7, Liége - 4000, Belgium
    • Dates

  • Journal of Biosciences | News

      Forthcoming Special issue.

    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".

      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.

      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.

      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

      Posted on April 12, 2023
    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2022-2023 Indian Academy of Sciences, Bengaluru.