• Role of nicotinic acid as modulator of liposomal microviscosity

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    • Keywords


      Nicotinic acid; phospholipid; fluidity; phase transition

    • Abstract


      Using the fluorescent probe 1,6-diphenyl-1,3,5 hexatriene, we have investigated the effect of nicotinic acid, a derivative of the toxic alkaloid nicotine, on the fluidity profile and activation energy of diffusion in the liposomal system of several lipids. We have also studied how the fluidizing property of nicotinic acid affects the intermediate fluid condition induced by cholesterol in these liposomal systems

    • Author Affiliations


      M Chatterjee1 2 R Basu1 P Nandy1

      1. Department of Physics, Jadavpur University, Calcutta - 700 032, India
      2. Guha Institute of Biochemistry, 55/5 Purna Das Road, Calcutta - 700 029, India
    • Dates

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