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    • Effect of epinephrine on thein vitro biosynthesis of fibrinogen

      A K Roy R Bhadra A G Datta

      Volume 14 Issue 4 December 1989 pp 379-383

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/014/04/0379-0383

    • Keywords

       

      Epinephrine; rat liver slice; fibrinogen; poly (A)+ RNA; stimulation; de novo synthesis

    • Abstract

       

      In anin vitro rat liver slice incubation system, the synthesis of fibrinogen, when measured by immunoprecipitation technique was stimulated in the presence of epinephrine. An increase in poly (A)+ RNA content of the liver slice was also observed after epinephrine treatment. Thisin vitro experiment demonstrated that epinephrine stimulatedde novo synthesis of fibrinogen by acting directly on the liver.

    • Author Affiliations

       

      A K Roy1 2 R Bhadra1 A G Datta1

      1. Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Calcutta - 700 032, India
      2. Department of Biological Chemistry, M. S. Hershy Med. CTN, 500 University Drive, Hershey, PA - 17033, USA

    • Dates

       
      Published
      December 1989
      Manuscript received
      1 July 1989
      Manuscript revised
      13 October 1989

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