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    • Keywords


      Human erythrocyte membrane; lanthanum; acetylcholinesterase; Arrhenius plot

    • Abstract


      Lanthanum chloride (1 mM) inhibits the activity of acetylcholinesterasein vitro in the human erythrocyte membrane. Lineweaver-Burk analysis indicates that lanthanum chloride induced inhibition of acetylcholinesterase activity is competitive in nature. The Arrhenius plot shows that the transition temperature of erythrocyte membrane-bound acetylcholinesterase is significantly reduced in the presence of lanthanum chloride. These results suggest that lanthanum chloride increases the fluidity of the erythrocyte membrane and this may be a cause of inhibition of membrane-bound acetylcholinesterase activity.

    • Author Affiliations


      Sunil Mukhopadhyay1 Sila Mukhopadhyay1 Dilip K Bhattacharyya1 2 Gora Chand Chatterjee1

      1. Department of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Calcutta - 700 019, India
      2. The Society for Research on Haematology and Blood Transfusion, Corporation Place, Calcutta - 700 087, India
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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