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      https://www.ias.ac.in/article/fulltext/jbsc/013/02/0123-0128

    • Keywords

       

      Human erythrocyte membrane; lanthanum; acetylcholinesterase; Arrhenius plot

    • Abstract

       

      Lanthanum chloride (1 mM) inhibits the activity of acetylcholinesterasein vitro in the human erythrocyte membrane. Lineweaver-Burk analysis indicates that lanthanum chloride induced inhibition of acetylcholinesterase activity is competitive in nature. The Arrhenius plot shows that the transition temperature of erythrocyte membrane-bound acetylcholinesterase is significantly reduced in the presence of lanthanum chloride. These results suggest that lanthanum chloride increases the fluidity of the erythrocyte membrane and this may be a cause of inhibition of membrane-bound acetylcholinesterase activity.

    • Author Affiliations

       

      Sunil Mukhopadhyay1 Sila Mukhopadhyay1 Dilip K Bhattacharyya1 2 Gora Chand Chatterjee1

      1. Department of Biochemistry, University of Calcutta, 35, Ballygunge Circular Road, Calcutta - 700 019, India
      2. The Society for Research on Haematology and Blood Transfusion, Corporation Place, Calcutta - 700 087, India
    • Dates

       
  • Journal of Biosciences | News

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