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    • Keywords


      Environmental factor; lipid composition; membrane structure; permeability; Microsporum gypseum

    • Abstract


      Supplementation with unsaturated fatty acids, substitution of glucose by glycerol as carbon source and lowered growth temperature (20°C) increased the total phospholipid content ofMicrosporum gypseum spheroplasts. Levels of sterols increased with glycerol substitution and decreased in other growth conditions. Substantial changes were seen in the ratios of unsaturated to saturated fatty acids and phosphatidylcholine to phosphatidylethanolafne under all the experimental conditions. Changed lipid composition resulted in altered uptake of amino acids (L-lysine, L-aspartic acid and L-glycine) and increased number of binding sites for a fluorescent probe, 1-anilinonaphthalene-8-sulfonate.

    • Author Affiliations


      Dipak Kapur1 Rakesh Pandey1 Seema Vaidya1 G K Khuller1

      1. Department of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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