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    • Keywords


      RNase; 2′,5′-oligoA synthetase activity; poly(I).poly(C) administration

    • Abstract


      The present study demonstrates the presence of considerable levels of 2′, 5′-oligoA synthetase activity in tissue extracts from mice. The interferon inducer, poly(I) .poly(C) , induced the synthetase activity in all the tissue extractsin vivo. Similarly, a significant amount of endonuclease RNase F activity is found to be present in these tissue extracts. But interferon induction does not seem to have any significant effect on RNase F activity.

    • Author Affiliations


      Krishna Baksi1 Boris Skurkovich1 Simon Skurkovich1

      1. Laboratory of Cell Biology and Genetics, National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland - 20205, USA
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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