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    • Keywords


      Autoregulation; rho gene; transcription termination

    • Abstract


      Autoregulation of therho gene insures a controlled level of a critical gene product independent of cellular changes. We have investigated the autoregulation ofrho, the gene that encodes the transcription termination factor,rho. In a DNA dependentin vitro coupled transcription-translation system,rho represses its own synthesis, confirming the autoregulatory nature ofrho. srho is believed to perform its negative regulatory role by modulating transcription termination at an early site in the operon.

    • Author Affiliations


      Roberta Haber1 Sankar Adhya1

      1. Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD - 20892, USA
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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