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      https://www.ias.ac.in/article/fulltext/jbsc/010/02/0227-0234

    • Keywords

       

      Acid lipase; alkaline lipase; hormone sensitive lipase; lipoprotein lipase; mandur bhasma; liver; kidney; adipose tissue; CCl4

    • Abstract

       

      ‘Mandur bhasma’, an ayurvedic preparation of iron is used in traditional medicine against hepatitis. In the present study the hepatoprotective property of this drug was tested in albino rats during CC14 induced hepatic injury. The effect of mandur bhasma on the activities of the lipolytic enzymes of rat liver, kidney and adipose tissue were studied during hepatitis induced by CCl4. The activities of acid lipase, alkaline lipase, lipoprotein lipase and hormone sensitive lipase exhibited significant alterations during CCl4 induced hepatic injury, indicating a role for these enzymes in the mobilization of fat from adipose tissue and accumulation of fat in liver and kidney. Simultaneous treatment with mandur bhasma prevented the paraffin mediated and CC14 mediated changes in the enzyme activities. These results suggest the hepatoprotective role of mandur bhasma during CCl4 induced hepatic injury.

    • Author Affiliations

       

      Pratibha Devarshi1 Aruna Kanase1 Ravindra Kanase1 Sadashiv Mane1 Subhash Patil1 A T Varute1

      1. Cell Biology Section, Zoology Department, Shivaji University, Kolhapur - 416004, India

    • Dates

       
      Published
      June 1986
      Manuscript received
      26 December 1984
      Manuscript revised
      16 December 1985

  • Journal of Biosciences | News

      Forthcoming Special issue.


    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".


      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.


      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.


      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

      Posted on April 12, 2023
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    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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