Polyadenylation of mRNA is a post-transcriptional phenomenon and is catalysed by both nuclear and cytoplasmic poly(A) polymerases. In rat testis the specific activity of cytoplasmic poly(A) polymerase increased with age reaching a peak value in 80 days. After this time the activity was maintained at a slightly lower level for the next 280 days. Follicle stimulating hormone, luteinizing hormone, human chorionic gonadotropin, pregnant mare serum gonadotropin and a gonadotropin releasing hormone analogue significantly increased the enzyme activity in immature rat testis. These results show that testicular poly(A) polymerase was probably under the influence of gonadotropic hormones.
Volume 45, 2020
Continuous Article Publishing mode
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