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    • Hormonal regulation of poly(A) polymerase in the testis of rat

      V S Raju P R K Reddy

      Volume 7 Issue 2 March 1985 pp 223-227

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/007/02/0223-0227

    • Keywords

       

      Testis; poly(A) polymerase; effect of gonadotropic hormones

    • Abstract

       

      Polyadenylation of mRNA is a post-transcriptional phenomenon and is catalysed by both nuclear and cytoplasmic poly(A) polymerases. In rat testis the specific activity of cytoplasmic poly(A) polymerase increased with age reaching a peak value in 80 days. After this time the activity was maintained at a slightly lower level for the next 280 days. Follicle stimulating hormone, luteinizing hormone, human chorionic gonadotropin, pregnant mare serum gonadotropin and a gonadotropin releasing hormone analogue significantly increased the enzyme activity in immature rat testis. These results show that testicular poly(A) polymerase was probably under the influence of gonadotropic hormones.

    • Author Affiliations

       

      V S Raju1 P R K Reddy1

      1. School of Life Sciences, University of Hyderabad, Hyderabad - 500 134, India

    • Dates

       
      Published
      March 1985
      Manuscript received
      13 December 1984

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