• Physiology of the epididymis and spermatozoa

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    • Keywords


      Epididymis; sialoproteins; androgen requirement; steroid metabolism

    • Abstract


      The epididymis is an ideal extragonadal target site to inhibit fertility in the male. Synthesis and secretion of constituents like sialic acids, protein and glycerylphosphoryl choline by the epididymal epithelium under androgen control provide an ideal fluid environment for sperm maturation. An optimal level of sialic acid secretion by the epididymal epithelium is needed to maintain functional integrity of sperm. The existence of specific androgen receptors in the epididymis and spermatozoa are related to their ability to metabolise androgens.

    • Author Affiliations


      M Rajalakshmi1

      1. Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi - 110 029, India
    • Dates

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