1. Home
    2. Journals
    3. Journal of Biosciences
    4. Volume 6
    5. Issue 6

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/006/06/0811-0816

    • Keywords

       

      Unilamellar liposomes; dextran conjugate; drug delivery

    • Abstract

       

      Dextran was covalently coupled to neutral unilamellar liposomes. Dextran conjugated liposomes were cleared from the circulation at a much slower rate than unconjugated liposomes. The uptake of dextran conjugated liposomes by liver and spleen was also decreased. The amount of dextran on the surface of liposomes was found to be a determining factor for their stability in circulation. Dextran conjugated liposomes therefore may be a more effective way of controlled drug release

    • Author Affiliations

       

      D Pain1 2 P K Das1 3 P Ghosh1 4 B K Bachhawat1

      1. Indian Institute of Chemical Biology, Calcutta - 700 032, India
      2. Laboratory of Cell Biology, The Rockefeller University, New York, New York - 10021, USA
      3. Developmental and Metabolic Neurology Branch, National Institutes of Health, Bethesda, MD - 20205, USA
      4. Department of Microbiology, Uniformed Services University Health Sciences, Bethesda, MD - 20814, USA

    • Dates

       
      Published
      December 1984
      Manuscript received
      16 March 1984
      Manuscript revised
      10 September 1984

  • Journal of Biosciences | News

      Forthcoming Special issue.


    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".


      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.


      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.


      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

      Posted on April 12, 2023
      <

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2023-2024 Indian Academy of Sciences, Bengaluru.

Contact | Site index