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    • Keywords


      Chyluria; humoral immunity; IgE

    • Abstract


      Humoral immune parameters like total immunoglobulins and specific antibody levels in serum were studied in filarial chyluria patients. Mean serum IgG was significantly reduced in this group compared to normal controls, while IgA and IgM levels remained comparable to controls. Anti-filarial antibody titre as measured by enzyme-linked immunosorbent assay also was significantly reduced. However, the total and specific IgE antibody titre was similar to that of controls. Specific IgE contents of the patients’ sera could be related to their microfilaraemic status.

    • Author Affiliations


      Alamelu Raja1 Rabia Hussain1 2 R Prabhakar1 P R Narayanan1

      1. Tuberculosis Research Centre, Madras - 600 031, India
      2. Laboratory of Parasitic Diseases, National Institute of allergy and Infectious Diseases, National Institute of Health, Bethesda, Maryland - 20205, USA
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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