• Haemolysis of rabbit erythrocytes by a lectin from the seeds ofCroton tiglium

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/005/S1/0121-0129

    • Keywords

       

      Lectin; haemolysis; Croton tiglium

    • Abstract

       

      The kinetics of haemolysis of rabbit erythrocytes byCroton tiglium lectin was studied as a function of concentration of the lectin and erythrocytes. The length of the prelytic period decreased with increasing lectin concentrations, indicating that the secondary events at the membrane which follow the binding of the lectin to cell surface carbohydrate receptors are accelerated at higher surface concentrations of the lectin. The rate or extent of haemolysis was not affected by the inclusion of ions like K+, Ca2+ and Mg2+ in the medium or by the substitution of ionic medium by a non-ionic medium. The inhibition of haemagglutination and haemolysis of rabbit red cells byCroton tiglium lectin by antilectin rabbit serum was observed. A possible mechanism of haemolysis by the lectin is discussed.

    • Author Affiliations

       

      Kalyan K Banerjee1 A Sen1

      1. Department of Chemistry, Bose Institute, 93/1 Acharya Prafulla Chandra Road, Calcutta - 700 009
    • Dates

       
  • Journal of Biosciences | News

© 2017-2019 Indian Academy of Sciences, Bengaluru.