• Lectins fromGriffonia simplicifolia seeds

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    • Keywords


      Lectin; Bandeiraea simplicifolia ; Griffonia simplicifolia ; isolectins; carbohydrate binding

    • Abstract


      The physical-chemical and carbohydrate binding specificity ofGriffonia simplicifolia I (GS I) isolectins, one of the 4 lectins isolated fromGriffonia simplicifolia seeds, are described.

      Association constants for the binding of methyl α- and β-D-galactopyranoside and methyl 2-acetamido-2-deoxy-α-D-galactopyranoside to the A4, A2 B2 and B4 isolectins are reported.

      Precipitation reactions of theGriffonia simplicifolia isolectins with guaran and type B blood group substance are described.

      The hypothesis that subunit B is a precursor of subunit A, a process involving proteolytic cleavage of the B subunit, was tested by conducting structural studies on the 2 subunits. The results indicated that the A and B subunits are probably products of 2 separate but closely related, possibly contiguous genes.

    • Author Affiliations


      Irwin J Goldstein1

      1. Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan - 48109, USA
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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