• Lectins fromGriffonia simplicifolia seeds

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/005/S1/0065-0071

    • Keywords

       

      Lectin; Bandeiraea simplicifolia ; Griffonia simplicifolia ; isolectins; carbohydrate binding

    • Abstract

       

      The physical-chemical and carbohydrate binding specificity ofGriffonia simplicifolia I (GS I) isolectins, one of the 4 lectins isolated fromGriffonia simplicifolia seeds, are described.

      Association constants for the binding of methyl α- and β-D-galactopyranoside and methyl 2-acetamido-2-deoxy-α-D-galactopyranoside to the A4, A2 B2 and B4 isolectins are reported.

      Precipitation reactions of theGriffonia simplicifolia isolectins with guaran and type B blood group substance are described.

      The hypothesis that subunit B is a precursor of subunit A, a process involving proteolytic cleavage of the B subunit, was tested by conducting structural studies on the 2 subunits. The results indicated that the A and B subunits are probably products of 2 separate but closely related, possibly contiguous genes.

    • Author Affiliations

       

      Irwin J Goldstein1

      1. Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan - 48109, USA
    • Dates

       
  • Journal of Biosciences | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2017-2019 Indian Academy of Sciences, Bengaluru.