• Fulltext


        Click here to view fulltext PDF

      Permanent link:

    • Keywords


      Circulating immune complexes; rodent malaria; simian malaria; Plasmodium berghei ; Plasmodium knowlesi

    • Abstract


      The circulating immune complexes have been detected in the sera of albino rats infected withPlasmodium berghei and rhesus monkeys infected with P.knowlesi by (i) quantitative cryoprecipitation assay and (ii) polyethylene glycol assay. In the rodent model, the levels of circulating immune complexes increased during infection and decreased considerably in the post-infection period. In the simian system, high levels were detected during peak parasitaemia. Polyethylene glycol precipitate obtained from the sera during acuteP. knowlesi infection when analysed by Immunoelectrophoresis was found to contain (i) monkey IgG, (ii) four other components of monkey plasma, (iii) two components of normal monkey erythrocytes and (iv) antigen(s) ofP. knowlesi.

    • Author Affiliations


      B Ravindran1 R R Sharma1 B K Sharma1 Q Z Hussain1

      1. Department of Biochemistry/Immunology, National Institute of Communicable Diseases, New Delhi - 110 054
    • Dates

  • Journal of Biosciences | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2017-2019 Indian Academy of Sciences, Bengaluru.