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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/004/03/0257-0261

    • Keywords

       

      Jack fruit seed; lectin; α-D-galactose; guar gum; affinity chromatography

    • Abstract

       

      An α-D-galactose-specific lectin from the seeds of jack fruit (Artocarpus integra) has been isolated in pure form by affinity chromatography on immobilised guar gum (a galactomannan). The lectin is shown to be a glycoprotein containing 3% carbohydrate and having a molecular weight of 39,500 as determined by gel filtration. Sodium dodecyl sulphate gel electrophoresis revealed a single polypeptide of 10,500 dalton, indicating that the native lectin is a tetrarner of identical subunits. The hemagglutinating activity of the lectin towards erythrocytes of all blood groups is found to be the same.

    • Author Affiliations

       

      G Suresh Kumar1 P S Appukuttan1 Debkumar Basu1

      1. Neurochemistry Division, Sree ChitraTirunal Institute for Medical Sciences and Technology, Trivandrum - 695 011
    • Dates

       
  • Journal of Biosciences | News

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      Posted on July 25, 2019

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