• Changes in DNA, RNA, protein and the activities of acid and alkaline DNases in developing and aging rat cerebellum

    • Fulltext


        Click here to view fulltext PDF

      Permanent link:

    • Keywords


      DNA; DNases; aging; rat; cerebellum

    • Abstract


      The content of DNA, RNA and protein in cerebellum at different stages of the life span of rat as well as the ratios of protein to DNA, showed-that in this region extensive cell proliferation occurs between the 1st and 7th day after birth and once again between the ages of 225 and 750 days. The putative DNA degrading enzymes, acid and alkaline DNases, showed a positive correlation with the rapid DNA accretion noticed during developmental stages as well as during old age. From these results, it could be presumed that there was a second bout of glial cell multiplication in aging cerebellum and that DNases must be playing some important role in the process.

    • Author Affiliations


      K V Subba Rao1 K Subba Rao1

      1. School of Life Sciences, University of Hyderabad, Hyderabad - 500 134
    • Dates

  • Journal of Biosciences | News

      Forthcoming Special issue.

    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".

      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.

      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.

      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

      Posted on April 12, 2023
    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2023-2024 Indian Academy of Sciences, Bengaluru.