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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/003/04/0379-0388

    • Keywords

       

      Benzanthrone; dye intermediate; uptake by the skin; serum transport

    • Abstract

       

      The uptake of benzanthrone by rat skin showed saturation kinetics and was dependent upon the weight of skin and time, temperature and pH of the incubation medium. Heating of segments above 50‡C caused significant lowering of the uptake. The uptake was irreversibly inhibited by HgCl2 and not by sodium arsenate, KCN, NaF,p-chloromercuriben zoate, N-ethyl-maleimide, cycloheximide, iodoacetic acid and 2,4-dinitrophenol suggesting that the uptake was not energy-dependent. Lipid micelles of the skin accounted for a part of the binding. Most of the benzanthrone taken up by the skin was effluxed through serum proteins.

    • Author Affiliations

       

      A Joshi1 S K Khanna1 G B Singh1 C R Krishna Murti1

      1. Industrial Toxicology Research Centre, Mahatma Gandhi Marg, Lucknow - 226 001

    • Dates

       
      Published
      December 1981
      Manuscript received
      3 June 1981
      Manuscript revised
      8 September 1981

  • Journal of Biosciences | News

      Forthcoming Special issue.


    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".


      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.


      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.


      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

      Posted on April 12, 2023
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    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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