• The binding of progesterone in different parts of the rabbit uterus during implantation

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    • Keywords

       

      Rabbit; uterus; progesterone; receptors

    • Abstract

       

      Progesterone receptors, both nuclear and cytosolic, were determined in the embryonic and inter-embryonic segments of the rabbit uterus at 6, 7 and 8 daypost-coitum. At day6 postcoitum a higher concentration of nuclear receptor in the embryonic segment was observed compared with that in the inter-embryonic segment. A reverse situation was observed in the case of cytoplasmic receptors. On the 7th daypost-coitum, no significant alteration in the concentration of either kind of the receptors was observed. However, on day 8, a higher concentration of both nuclear and cytosolic receptors at the embryonic site was observed compared to that in inter-embryonic segment. Since receptors are influenced only in the immediate vicinity of the blastocyst, it can be suggested that the blastocyst plays a role in the induction of its own implantation. Further, at day 8 increase in receptor concentration at the embryonic site may be related to the presence of decidual tissue at this site.

    • Author Affiliations

       

      Raj K Puri1 S K Roy1

      1. Division of Endocrinology, Central Drug Research Institute, Lucknow - 226 001
    • Dates

       
  • Journal of Biosciences | News

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