• Age-related qualitative and quantitative changes in tRNA population of rat skeletal muscle

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    • Keywords


      Rat; skeletal muscle; tRNA; aging; aminoacylation; aminoacyl-tRNA fractionation

    • Abstract


      Total tRNA was purified from skeletal muscle of young, adult and old female albino rats. Age-dependent variation of total tRNA was the same with respect to tRNA content and biological activity as measured by amino acid acceptor capacity. The tRNA content was more in young rats and showed a gradual decrease in the adult and old rats. The relative abundancy of eleven aminoacyl-tRNAs were checked at each age and during aging. Arginyl, glutamyl and tyrosyl-tRNAs do not show any quantitative or qualitative change with age.

    • Author Affiliations


      Manjula1 R M Sundari1

      1. Biochemistry Laboratory, Department of Zoology, Banaras Hindu University, Varanasi - 221 005
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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