• Preliminary studies on the toxicity and mutagenicity of 1-amino-2-naphthol-4-sulphonic acid inDrosophila melanogaster

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    • Keywords

       

      1-Amino-2-naphtho-4-sulphonic acid; Drosophila melanogaster ; rate of develop-ment; viability; dominant lethals

    • Abstract

       

      The toxicity and mutagenicity of 1-amino-2-naphtho-4-sulphonic acid were analysed inDrosphila melanogaster. Rate of development and viability were the two parameters employed to study the toxicity. The frequency of dominant lethals was scored to evaluate the mutagenic effect of the chemical on male and female germ cells. Concentrations of 250 mg and above/100 ml wheat cream agar medium were found to be significantly toxic. Significant number of dominant lethals was induced even by a concentration as low as 50 mg/100 ml medium. Male germ cells were more sensitive than female germ cells.

    • Author Affiliations

       

      M V Gayathri1 N B Krishnamurthy1

      1. Department of Post-Graduate Studies and Research in Zoology, University of Mysore, Manasa-gangotri, Mysore - 570 006
    • Dates

       
  • Journal of Biosciences | News

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