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    • Keywords


      Actinomycete; L-dihydroxyphenylalanine production; fermentation

    • Abstract


      An actinomycete was isolated during a soil screening programme to obtain L-3,4-dihydroxyphenylalanine producers. A mutant of this organism was isolated by chemical mutagenesis and it accumulated 1 g/litre L-dihydroxyphenylalanine when grown on L-tyrosine. Resting cells converted 30% of tyrosine in the reaction mixture. The use of resting cells for dihydroxyphenylalanine production is advantageous as it eliminates interfering substances which accumulate during fermentation.

    • Author Affiliations


      C P Sukumaram1 D V Singh1 P D Khedkar1 P R Mahadevan1 2

      1. Central Research Laboratory, Indian Drugs and Pharmaceuticals Limited, Rishikesh, Virbhadra - 249 202
      2. Foundation for Medical Research, 84-A, R. G. Thadani Marg, Bombay - 400018
    • Dates

  • Journal of Biosciences | News

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      Posted on July 25, 2019

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