• Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/001/02/0235-0239

    • Keywords

       

      Actinomycete; L-dihydroxyphenylalanine production; fermentation

    • Abstract

       

      An actinomycete was isolated during a soil screening programme to obtain L-3,4-dihydroxyphenylalanine producers. A mutant of this organism was isolated by chemical mutagenesis and it accumulated 1 g/litre L-dihydroxyphenylalanine when grown on L-tyrosine. Resting cells converted 30% of tyrosine in the reaction mixture. The use of resting cells for dihydroxyphenylalanine production is advantageous as it eliminates interfering substances which accumulate during fermentation.

    • Author Affiliations

       

      C P Sukumaram1 D V Singh1 P D Khedkar1 P R Mahadevan1 2

      1. Central Research Laboratory, Indian Drugs and Pharmaceuticals Limited, Rishikesh, Virbhadra - 249 202
      2. Foundation for Medical Research, 84-A, R. G. Thadani Marg, Bombay - 400018
    • Dates

       
  • Journal of Biosciences | News

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2017-2019 Indian Academy of Sciences, Bengaluru.