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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/jbsc/001/02/0143-0149

    • Keywords

       

      Neurospora crassa ; copper toxicity; histidine biosynthesis; histidinol phosphate phosphatase

    • Abstract

       

      The inhibition of growth of a wild strain ofNeurospora crassa by Cu2+ is counteracted by histidine, histidine methyl ester, histidinol and Mn2+. In the presence of Cu2+, the total free amino acid content decreased by 30%. The decreased free amino acid pools of arginine, histidine and tyrosine were restored on the addition of Mn2+. Histidinol phosphate phosphatase showed a decrease in activity in the presence of Cu2+. This inhibition was reversed on the addition of excess Mn2+. The data suggest that copper toxicity in the mould is due to suppression of histidine biosynthesis.

    • Author Affiliations

       

      C Subramanyam1 G Venkateswerlu1

      1. Department of Biochemistry, Osmania University, Hyderabad - 500 007

    • Dates

       
      Published
      June 1979
      Manuscript received
      26 December 1978
      Manuscript revised
      10 March 1979

  • Journal of Biosciences | News

      Forthcoming Special issue.


    • To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".


      Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.


      Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.


      Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx

      Posted on April 12, 2023
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    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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