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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/046/0105

    • Keywords

       

      Vertical graphene (VG); PECVD; EIS; cell culture; MTT.

    • Abstract

       

      Vertical graphene (VG) is one of the newest forms of graphite, being part of the family of carbon materials. Due to its unique characteristics and physiochemical properties including large specific surface area, high electric conductivity and intense electrochemical activity, it has attracted the interest in many applications, specifically in the medical field. VG is a two-dimensional graphitic sheet, vertically aligned to the substrate. Its electrical characteristics make VG a good choice for using it in the development of electrochemical biosensors for cellular identification. VG is obtained using plasma enhanced chemical vapor deposition. Scanning electron microscopy was used to study the morphological structure of the grown vertical graphene, Raman spectroscopy was performed to identify the characteristic vibrational modes and to assess the quality of the deposited films and electrochemical impedance spectroscopy was used for electrical characterization of the vertical graphene. In order to assess the biological effect of VG samples and to confirm that the VG can be used for cellular identification, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium-salt assay was used on a cell line of U251 human glioblastoma (CLS).

    • Author Affiliations

       

      E ANGHEL1 2 B ADIACONITA3 A AVRAM3 C MIHAILESCU3 C PACHIU3 O BRINCOVEANU3 R C POPESCU4 I DEMETRESCU2 5

      1. Extreme Light Infrastructure–Nuclear Physics, 077125 Magurele, Romania
      2. Faculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 011061 Bucharest, Romania
      3. National Institute for Research and Development in Microtechnologies–IMT Bucharest, 077190 Bucharest, Romania
      4. Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering, 077125 Magurele, Romania
      5. Academy of Romanian Scientists, 030167 Bucharest, Romania

    • Dates

       
      Published
      22 May 2023
      Manuscript received
      8 July 2022
      Accepted
      26 December 2022
      Final version published online
      22 May 2023

  • Bulletin of Materials Science | News

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      Posted on October 12, 2020

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      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
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    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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