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https://www.ias.ac.in/article/fulltext/boms/045/0211 -
Keywords
Nanoparticles ;electrodeposition ;Raman ;SERS ;Tobramycin ;drug detection. -
Abstract
Sensitive surface-enhanced Raman spectroscopy (SERS) substrates designed for drug sensing are in great interest due to the growing demand in environmental monitoring, disease therapies and chemical analysis. Here, spherical silver nanoparticles (Ag-NPs; ${\sim}$8 nm) are synthesized via a simple electrochemical route and examined as SERS substrates for Tobramycin (TOBi) detection. The morphology and structure characterizations confirm the successful fabrication of Ag-NP. TOBi in diluted solution has a detection limit of 10$^{-6}$ M, and the linear relationship between SERS intensity and TOBi amount is between 10$^{-6}$ and 10$^{-5}$ M. A strong SER signal with an enhancement factor of ${\sim}$7.5 ${\times}$ 10$^4$ is observed. TOBi drug is for the first time investigated through Ag-based SERS detection.
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Graphical Abstract
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Author Affiliations
HAFSA SIDDIQUI1 NETRAPAL SINGH1 2 RASHEDA KHAN3 RITU SHARMA4 MANOJ GOSWAMI1 2 SATENDRA KUMAR1 2 SUNEEL KUMAR1 N SATHISH1 2 SHIV SINGH PATEL1 2 MOHD AKRAM KHAN1 2 SURENDER KUMAR1 2
- CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal 462026, India
- Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India
- Department of Biotechnology, SAM Girls College, Bhopal 462023, India
- Department of Biotechnology, Sathya Sai Autonomous College for Women, Bhopal 462024, India
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Dates
- Published
- 26 October 2022
- Manuscript received
- 25 March 2022
- Accepted
- 20 June 2022
- Final version published online
- 26 October 2022
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Bulletin of Materials Science
Volume 46, 2023
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