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    • Advances in drug delivery and biomedical applications of hydroxyapatite-based systems: a review

      AREZOU MASHAK SAEED BAZRAEE HAMID MOBEDI

      Volume 45 Published: 21 September 2022 Article ID 0183

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/045/0183

    • Keywords

       

      Hydroxyapatite; hydroxyapatite composites; drug delivery systems; bioceramic; antibacterial agents; metal doped.

    • Abstract

       

      The application of biomaterials such as biopolymers and bioceramics is developed in tissue engineering and drug delivery fields. Hydroxyapatite (HAp) is considered one of the essential bioceramics due to its suitable properties,such as biocompatibility and similarity to the mineral composition of bone. This review article focuses on some recent advances in drug delivery systems and tissue engineering in which HAp had played a significant role. These systems are divided into HAp -based systems, HAp composites, metal-doped HAp, and 3D-printed systems. However, the review will summarize the most common HAp preparation methods and introduce the different kinds of drugs loaded in the HAp based drug delivery systems.

    • Author Affiliations

       

      AREZOU MASHAK1 SAEED BAZRAEE1 2 HAMID MOBEDI1

      1. Department of Novel Drug Delivery Systems, Iran Polymer and Petrochemical Institute, P.O. Box: 14965/115, Tehran, Iran
      2. Varian Pharmed Co., P.O. Box: 1966834944, Tehran, Iran

    • Dates

       
      Published
      21 September 2022
      Manuscript received
      13 February 2022
      Accepted
      17 May 2022
      Final version published online
      21 September 2022

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