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https://www.ias.ac.in/article/fulltext/boms/045/0057 -
Keywords
ZnO nanorods ;PT–ZnO nanocomposite ;electrostatic interaction ;L-tryptophan ;electrochemical biosensor ;peanut extract. -
Abstract
Electrostatically fused nanocomposite of zinc oxide (ZnO) nanorods affixed with polythiophene (PT) was successfully illustrated for effective voltammetric biosensing of L-tryptophan (L-Try) in this work. Structural characterization confirms the in-situ composite formation of PT @ ZnO and its BET analysis reveals the porous nature of as-synthesized material having the specific surface area of 4.953 m$^2$ g$^{–1}$ and average pore diameter of 2.153 nm, respectively. PT @ ZnO exhibits superior electrochemical performance towards L-Try in phosphate buffer solution of pH 7 by the movement of fast electron-transfer rate because of effective interaction between indole group of L-Try and PT @ ZnO nanocomposite. That is, the sulphur group in PT easily attached with the amine group of L-Try demonstrated the linear increase of peak current with increasing concentration in the range of L-Try 100 nM$^{–1}$ mM having detection limit of 8.5 nM. The invented biosensor shows extraordinary selectivity among other physiological substances and also exposes high stability, repeatability and reproducibility. The practical utility of PT-ZnO/glassy carbon electrode tested with the concentration of L-Try in peanut extract showed preferable results.
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Graphical Abstract
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Author Affiliations
S DHEEPTHI GUNAVATHANA1 S GIRIJA2 J WILSON2 A CYRAC PETER1
- Department of Physics, Raja Doraisingam Government Arts College, Affiliated to Alagappa University, Karaikudi 630 561, India
- Department of Bioelectronics and Biosensors, Alagappa University, Karaikudi 630 001, India
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Dates
- Published
- 19 March 2022
- Manuscript received
- 29 July 2021
- Accepted
- 11 November 2021
- Final version published online
- 19 March 2022
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Supplementary Material
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Bulletin of Materials Science
Volume 46, 2023
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