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    • Keywords


      Bionanocatalyst; silver; characterization; sol–gel; antineoplastic.

    • Abstract


      In this study, bionanocatalysts composed of a titanosilicate oxide matrix (TiO$_2$–SiO$_2$) impregnated with different concentrations of silver (0.1, 0.5, 1.0, 5.0 and 10 wt%) were prepared by the sol–gel method using silver nitrate(AgNO$_3$) as silver (Ag) source. The physicochemical properties were evaluated by scanning and transmission electron microscopies, Raman and Fourier transform infrared spectra, X-ray photoelectron spectra, and UV–visible spectroscopy.Furthermore, we studied the cytotoxic effect on a cervical uterine cancer cell line as a first approach attending to the potential antineoplastic properties of the Ag/TiO$_2$–SiO$_2$ bionanocatalysts. The bionanocatalysts exhibited no significant differences in morphology or composition independently of the amount of Ag stabilized, with a reduction in particle size proportional to Ag concentration. All samples could achieve cell mortality rates above 91%, obtaining results similar tothose of pure AgNO$_3$ (considered as 100% Ag) from the sample loaded with 1% Ag. The results in this study suggest the possibility of using bionanocatalysts to enhance the intrinsic cytotoxic properties of silver such that a minimum concentration is required to achieve desired results.

    • Author Affiliations



      1. Department of Health Care, Autonomous Metropolitan University - Xochimilco, 04960 Mexico City, Mexico
      2. Institute of Cellular Physiology, National Autonomous University of Mexico, 04510 Mexico City, Mexico
      3. Department of Mathematical, Physical and Computer Sciences, University of Parma, 43121 Parma, Italy
      4. Advanced Materials Laboratory, Alicante University, 03690 Alicante, Spain
    • Dates

  • Bulletin of Materials Science | News

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      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
      Physical Sciences 2020

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

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