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      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/044/0214

    • Keywords

       

      Biomolecules; carbon nanoparticle; red fluorescence; bioconjugation; bioimaging.

    • Abstract

       

      Although wide variety of molecular precursors have been used for carbonization-based synthesis of fluorescent carbon nanoparticle, biomolecule-derived carbon nanoparticle with tunable fluorescence is difficult to synthesize. Here, we report a generalized approach for the preparation of fluorescent carbon nanoparticle from various biomolecules, such as lactose, ascorbic acid, tyrosine and sucrose. The method involves controlled carbonization of molecular precursor in ethylene glycol at 190°C in the presence of Na$_3$PO$_4$. The presented synthetic method can produce 20–30 mg of nanoparticles in one batch with fluorescence quantum yield in the range of 1–10% and nanoparticles can be conjugated with primary amine-terminated chemical/biochemical by simple incubation. These fluorescent carbon nanoparticles can be transformed into different nanobioconjugates for various biomedical applications.

    • Author Affiliations

       

      SANTU GHOSH1 HAYDAR ALI1 SUMAN PAL1 SEKHAR C RAY2 NIKHIL R JANA1

      1. School of Materials Science, Indian Association for the Cultivation of Science, Kolkata 700032, India
      2. Department of Physics, CSET, University of South Africa, 1710, Science Campus, Christiaan de Wet and Pioneer Avenue, Park, Private Bag X6, Johannesburg, South Africa

    • Dates

       
      Published
      19 July 2021
      Manuscript received
      2 February 2021
      Accepted
      7 March 2021
      Final version published online
      19 July 2021

    • Supplementary Material

       

  • Bulletin of Materials Science | News

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      Posted on October 12, 2020

      Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
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      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
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    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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