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      https://www.ias.ac.in/article/fulltext/boms/044/0197

    • Keywords

       

      Oligopeptide; microphase separation; self-assembly; liquid crystalline.

    • Abstract

       

      Tissue-engineered vascular grafts are increasing in popularity in the treatment of cardiovascular disease. However, poor mechanical strength, brittle texture and other defects restrict their extensive application. In the present work, oligopeptide hybrid films were prepared by L-tyrosine-derivative oligopeptide (TEA), polyethylene glycol (PEG) and polyvinyl alcohol (PVA). The films were prepared with different PEG molecular weights and TEA contents. The chemical structures were characterized using Fourier-transform infrared spectroscopy, while the micromorphology and self-assembly behaviour were examined using scanning electron microscopy and differential scanning calorimetry. The mechanical properties of the films were investigated, and the cellular behaviour was observed using polarized optical microscopy. The experimental results indicated that the degree of microphase separation depended on the molecular weight of the PEG and TEA content. The biocompatibility of the films improved as the TEA content increased. The liquid crystalline properties of the TEA affected

    • Author Affiliations

       

      CHUANJUN XIA1 PINGDENG MING1 ANDUO ZHOU1 SHANFENG ZHANG2 JUYING CHEN3 XIA HUANG1

      1. School of Materials Science and Engineering, Zhengzhou University, Zhengzhou, Henan 450001, People’s Republic of China
      2. School of Basic Medical Science, Zhengzhou University, Zhengzhou, Henan 450001, People’s Republic of China
      3. Zhengzhou University, Zhengzhou, Henan 450001, People’s Republic of China
    • Dates

       
  • Bulletin of Materials Science | News

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