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    • Thymol-functionalized hollow mesoporous silica spheres nanoparticles: preparation, characterization and bactericidal activity

      YUHAO LIU LI JIN CHEN WANG JIE SHENG YISHAN SONG

      Volume 44 Published: 30 April 2021 Article ID 0126

    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/044/0126

    • Keywords

       

      Thymol; hollow mesoporous silica spheres; bactericidal activity.

    • Abstract

       

      Antimicrobial natural products show good antimicrobial activities; however, some of them have unpleasant odor or high volatility that limits their application in food industry. One of solutions is to introduce them in inorganic media. In this study, hollow mesoporous silica sphere (HS) was used to encapsulate natural organic antimicrobial agent thymol, and antimicrobial activity of the resulted antimicrobial agent (HST) was tested. Materials characterization revealed that the thymol was successfully introduced into the cavities of HS, and the inorganic host exhibited a high loading capacity of 1320 mg g$^{-1}$. In addition, the antibacterial activities were tested by double-fold dilution method, the minimum bactericidal concentrations of HST against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were decreased compared with that of thymol. Furthermore, scanning electron microscopy observation confirmed that HST indeed showed a notable inhibitory effect against E. coli and S. aureus by disrupting cell membrane structure.

    • Author Affiliations

       

      YUHAO LIU1 LI JIN1 CHEN WANG1 JIE SHENG1 YISHAN SONG1 2

      1. College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China
      2. College of Food Science and Technology, Laboratory of Quality and Safety Risk Assessment for Aquatic Products on Storage and Preservation (Shanghai), Ministry of Agriculture and Shanghai Engineering Research Center of Aquatic- Product Processing and Preservation, Shanghai Ocean University, Shanghai 201306, China

    • Dates

       
      Published
      30 April 2021
      Manuscript received
      22 August 2020
      Accepted
      20 January 2021
      Final version published online
      30 April 2021

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