Here, we developed an impedimetric nanosensor by modifying the screen-printed carbon electrode using ananocomposite of molecularly imprinted polyaniline/gold nanoparticles/graphene oxide to facilitate the charge transferprocess and increase the specific surface area of the sensor. The electropolymerization and MIP fabrication process, as well asthe optimization of the electrode modification were optimized using a set of experiments. The surface morphology of themodified electrode was characterized by field emission scanning electron microscopy, energy dispersive spectroscopy andelectrochemical impedance spectroscopy. The analytical assessments of the bupropion hydrochloride (BUP) electrochemical nanosensor showed a linear range from 2.0 to 990.0 nM with the limit of detection of 0.5 nM. The results of selectivity tests of the nanosensor showed a high specificity towards BUP compared to other similar molecules. Furthermore, the developed sensor was successfully applied to detect BUP in tablets and urine samples with a good recovery percentage.
Volume 45, 2022
Continuous Article Publishing mode
Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
Chemical Sciences 2020
Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
Physical Sciences 2020
Click here for Editorial Note on CAP Mode