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    • Fulltext

       

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      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/044/0056

    • Keywords

       

      Electrochemical; sensor; nanocomposite; bupropion.

    • Abstract

       

      Here, we developed an impedimetric nanosensor by modifying the screen-printed carbon electrode using ananocomposite of molecularly imprinted polyaniline/gold nanoparticles/graphene oxide to facilitate the charge transferprocess and increase the specific surface area of the sensor. The electropolymerization and MIP fabrication process, as well asthe optimization of the electrode modification were optimized using a set of experiments. The surface morphology of themodified electrode was characterized by field emission scanning electron microscopy, energy dispersive spectroscopy andelectrochemical impedance spectroscopy. The analytical assessments of the bupropion hydrochloride (BUP) electrochemical nanosensor showed a linear range from 2.0 to 990.0 nM with the limit of detection of 0.5 nM. The results of selectivity tests of the nanosensor showed a high specificity towards BUP compared to other similar molecules. Furthermore, the developed sensor was successfully applied to detect BUP in tablets and urine samples with a good recovery percentage.

    • Author Affiliations

       

      SAEID JAFARI1 MOHAMMAD DEHGHANI1 NAVID NASIRIZADEH1 MOSTAFA AZIMZADEH2 3 4 FATEMEH DEHGHAN BANADAKI5

      1. Department of Textile and Polymer Engineering, Yazd Branch, Islamic Azad University, PO Box: 89195-155, Yazd, Iran
      2. Medical Nanotechnology and Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, PO Box: 89195-999, Yazd, Iran
      3. Stem Cell Biology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, PO Box: 89195-999, Yazd, Iran
      4. Department of Advanced Medical Sciences and Technologies, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, PO Box: 8916188635, Yazd, Iran
      5. Department of Entrepreneurship Management, e-Campus Branch, Islamic Azad University, PO Box: 89195-155, Tehran, Iran

    • Dates

       
      Published
      8 March 2021
      Manuscript received
      14 June 2020
      Accepted
      12 October 2020
      Final version published online
      8 March 2021

  • Bulletin of Materials Science | News

    • Dr Shanti Swarup Bhatnagar for Science and Technology

      Posted on October 12, 2020

      Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
      Chemical Sciences 2020

      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
      Physical Sciences 2020

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

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