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      https://www.ias.ac.in/article/fulltext/boms/043/0091

    • Keywords

       

      Chitosan; hydroxyapatite; hybrid material; nanoparticles.

    • Abstract

       

      Hydroxyapatite nanoparticles were synthesized using modified sol–gel approach. Its biocompatibility was proved by in vitro experiments with diploid fibroblasts. The experiment showed that the presence of hydroxyapatite in the environment of cells does not reduce their viability. The observed phase transition of hydroxyapatite was explained as order/disorder transition, saving the crystal structure symmetry. Organo–inorganic composites of chitosan and hydroxyapatite were obtained by preparing a joint solution and pouring onto a glass substrate. According to XRD and DTA data, addition ofhydroxyapatite reduces the softening and decomposition temperature of chitosan. This information is necessary to optimize the manufacturing processes of organo–inorganic scaffolds.

    • Author Affiliations

       

      EVGENY BULANOV1 NADEZHDA SILINA1 MAXIM LELET1 ALEXANDER KNYAZEV1 LARISA SMIRNOVA1 DIANA ALEYNIK2 IRINA CHARYKOVA2

      1. Lobachevsky University, Nizhny Novgorod 603950, Russia
      2. Privolzhsky Research Medical University, Nizhny Novgorod 603005, Russia
    • Dates

       
  • Bulletin of Materials Science | News

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