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Synthesis and evaluation of antibacterial properties of magnesium oxide nanoparticles
JOYSHREE MAJI SANJEEV PANDEY SOUMEN BASU
Volume 43 Published: 3 January 2020 Article ID 0025
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https://www.ias.ac.in/article/fulltext/boms/043/0025 -
Keywords
MgO nanoparticle ;sol–gel method ;antibacterial activity. -
Abstract
In this paper we studied the efficiency of magnesium oxide (MgO) nanoparticles with an average size of 27 nm synthesized by a simple soft chemical method, in killing both Gram negative and Gram positive pathogenic bacteria. The antibacterial activity was determined by a minimum inhibitory concentration technique, agar cup method and live count technique. These nanoparticles show the maximum antibacterial activity towards Bacillus sp. in comparison with Escherichia coli. Transmission electron microscopy analyses of the treated-bacterial strains showed a morphological deformation with increased cell wall disruption. From the analysis of the antibacterial activity of MgO nanoparticles it is revealed that6 $\mu$g ml$^{−1}$ of dose is sufficient for killing Bacillus sp. whereas it is 7.5 $\mu$g ml$^{−1}$ for E. coli. These doses may be used in medical application. MgO nanoparticles could be used as antibacterial agents after completion of successful in vivo trials.
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Author Affiliations
JOYSHREE MAJI1 SANJEEV PANDEY2 SOUMEN BASU1
- Department of Physics, National Institute of Technology, Durgapur 713209, India
- Department of Botany, Banwarilal Bhalotia College, Asansol 713303, India
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Dates
- Published
- 3 January 2020
- Manuscript received
- 19 December 2018
- Accepted
- 8 June 2019
- Final version published online
- 18 December 2019
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Bulletin of Materials Science
Volume 46, 2023
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