• Superoxide dismutase mimic activity of spinel ferrite MFe$_2$O$_4$ (M $=$ Mn, Co and Cu) nanoparticles

    • Fulltext

       

        Click here to view fulltext PDF


      Permanent link:
      https://www.ias.ac.in/article/fulltext/boms/042/03/0120

    • Keywords

       

      Ferrite nanoparticles; enzyme mimics; superoxide dismutase mimic.

    • Abstract

       

      In the present study, superoxide dismutase (SOD) mimic activity of ferrite nanoparticles (NPs), having a formula MFe$_2$O$_4$ (M $=$ Mn, Co and Cu) was investigated. Spinel ferrite NPs were synthesized by employing sol–gelmethodology and characterized using scanning electron microscopy, X-ray diffraction, BET analysis and Fourier transform infrared spectroscopy techniques. BET analysis revealed that the surface area of ferrite NPs ranged from 0.43−23.49 m$2^$ g$^{−1}$. Enzyme mimic activity was compared using SOD as a model enzyme. CuFe$_2$O$_4$ NPs exhibited a maximum activity followedby CoFe$_2$O$_4$ and MnFe$_2$O$_4$ NPs. The results were correlated with a facile interconversion of the oxidation state leading to a stable electronic configuration in CuFe$_2$O$_4$ NPs. Optimum pH and contact time was 1 and 3 min respectively. Kinetic studies were performed under optimum conditions and data were analysed using the Michaelis Menten equation. The valuesof $V_{\rm max}$ (0.77 s$^{−1}$) and Km (4.20 mM) proved CuFe$_2$O$_4$ NPs as potential SOD mimic for a wide range of applications.

    • Author Affiliations

       

      VIBHA VERMA1 MANPREET KAUR1 SUCHETA SHARMA2

      1. Department of Chemistry, Punjab Agricultural University, Ludhiana 141 004, India
      2. Department of Biochemistry, Punjab Agricultural University, Ludhiana 141 004, India
    • Dates

       
  • Bulletin of Materials Science | News

    • Dr Shanti Swarup Bhatnagar for Science and Technology

      Posted on October 12, 2020

      Prof. Subi Jacob George — Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bengaluru
      Chemical Sciences 2020

      Prof. Surajit Dhara — School of Physics, University of Hyderabad, Hyderabad
      Physical Sciences 2020

    • Editorial Note on Continuous Article Publication

      Posted on July 25, 2019

      Click here for Editorial Note on CAP Mode

© 2021-2022 Indian Academy of Sciences, Bengaluru.