• Thioglycolic acid-capped CdS quantum dots modified with Co$^{2+}$ as a fluorescent sensor for dopamine

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      https://www.ias.ac.in/article/fulltext/boms/041/04/0109

    • Keywords

       

      Fluorescent sensors; quantum dots; fluorescent quenching; dopamine.

    • Abstract

       

      A new selective fluorescent sensor for detection of dopamine (DA) using Co$^{2+}$ -decorated thioglycolic acidcapped CdS QDs (Co$^{2+}$@TGA–CdS QDs) was proposed. Basically, the fluorescent intensity of TGA–CdS QDs can bequenched by Co$^{2+}$. However, with the addition of dopamine into the solution of Co$^{2+}@TGA–CdS QDs, the fluorescent intensity was efficiently quenched due to the formation of the efficient quencher (Co$^{2+}$–dopamine complex). Thus, the concentration of dopamine can be determined by tracking the decrease in the fluorescent intensity of the Co$^{2+}$@TGA–CdSQDs. The proposed sensor showed high selectivity towards the detection of dopamine over other catecholamine derivatives and related compounds. Under optimal conditions, the quenching efficiency of dopamine on the Co$^{2+}$@TGA–CdS QDs system was linearly proportional to the concentration of dopamine in the range of 20−100 $\mu$mol l$^{−1}$. The limits of detectionand quantification were 1.8 and 12.7 $\mu$mol l$^{−1}$, respectively. This sensor system was demonstrated to detect dopamine in real urine samples with satisfactory results.

    • Author Affiliations

       

      TUANJAI NOIPA1 2 WITTAYA NGEONTAE1 3 4

      1. Materials Chemistry Research Center, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand
      2. Faculty of Science and Engineering, Kasetsart University, Chalermphrakiat Sakon Nakhon Province Campus, Sakon Nakhon 47000, Thailand
      3. Research Center for Environmental and Hazardous Substance Management, Khon Kaen University, Khon Kaen 40002, Thailand
      4. Center of Excellence for Environmental and Hazardous Waste Management (EHWM), Bangkok 10330, Thailand
    • Dates

       
  • Bulletin of Materials Science | News

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