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      https://www.ias.ac.in/article/fulltext/boms/041/04/0093

    • Keywords

       

      Hydrothermal; hydroxyapatite; alumina; composite; biocompatibility.

    • Abstract

       

      In the present work, nanocrystalline hydroxyapatite/alumina (HAp−Al$_2$O$_3$) composite was prepared under specially designed stir-type hydrothermal reactor. The composite was prepared at two different temperatures under autogenous pressure and analysed for crystallinity, size, shape, composition and thermomechanical stability. The electron microscopy study shows the formation of HAp−Al$_2$O$_3$ composite nanorods with uniform distribution. The thermogravimetry analysis reveals better thermomechanical property with minimal weight loss at increased temperature. The effect ofdifferent concentrations of HAp−Al$_2$O$_3$ composite powders against MG63 human osteosarcoma cell lines shows excellent compatibility (80%) at high concentration of 200 $\mu$g ml$^{−1}$. These studies facilitate the formation of biocompatible HAp−Al$_2$O$_3$ composite nanorods for biomedical applications.

    • Author Affiliations

       

      S VIGNESH RAJ1 M RAJKUMAR2 N MEENAKSHI SUNDARAM3 A KANDASWAMY1

      1. Department of Biomedical Engineering, PSG College of Technology, Coimbatore 641004, India
      2. Department of Physics, PSG College of Arts and Science, Coimbatore 641014, India
      3. Department of Physics, LRG Government Arts College for Women, Tiruppur 641604, India
    • Dates

       
  • Bulletin of Materials Science | News

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