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      https://www.ias.ac.in/article/fulltext/boms/038/04/1069-1078

    • Keywords

       

      Clay mineral; drug carrier; intercalation; XRD; FTIR.

    • Abstract

       

      This paper focusses on the intercalation of clay mineral with gentamicin (an aminoglycoside antibiotic). The smectite clay–gentamicin hybrids were prepared by a solution intercalation at 60°C and the process was carried out on unmodified smectite clay and on smectite after Na+ ionic activation. The resulting structural/microstructural properties and the potential for introducing gentamicin between smectite clay layers were investigated by means of X-ray diffraction, Fourier transform infrared spectroscopic techniques and transmission electron microscopy and scanning electron microscopy with energy-dispersive spectroscopy X-ray analysis. The results confirm the successful intercalation of gentamicin into the interlayer space of smectite clay, demonstrating that the material thus obtained could potentially be used as a drug carrier.

    • Author Affiliations

       

      Alicja Rapacz-Kmita1 Ewa Stodolak-Zych1 Magdalena Ziabka1 Agnieszka Rozycka1 Magdalena Dudek2

      1. AGH University of Science and Technology, Faculty of Materials Science and Ceramics, Cracow 30-059, Poland
      2. AGH University of Science and Technology, Faculty of Energy and Fuels, Cracow 30-059, Poland
    • Dates

       
  • Bulletin of Materials Science | News

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